https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 The association between genetic polymorphisms in ABCG2 and SLC2A9 and urate: an updated systematic review and meta-analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38721 Wed 19 Jan 2022 09:36:02 AEDT ]]> Genetic associations of Nrf2-encoding NFE2L2 variants with Parkinson s disease a multicenter study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19339 A, −1.0 years per allele, p = 0.042; rs35652124 A > G, −1.1 years per allele, p = 0.045; rs2886161 A > G, −1.2 years per allele, p = 0.021; rs1806649 G > A, +1.2 years per allele, p = 0.029). One of these (rs35652124) is a functional SNP located in the NFE2L2 promoter. No individual SNP was associated with risk of Parkinson’s disease. Conclusion: Our results support the hypothesis that variation in the NFE2L2 gene, encoding a central protein in the cellular protection against oxidative stress, may contribute to the pathogenesis of Parkinson’s disease. Functional studies are now needed to explore these results further.]]> Wed 11 Apr 2018 14:07:28 AEST ]]>